This address begins by focusing on the issue of health inequities associated with regional, rural and remote communities including mortality and morbidity rates with specific reference to both physical and mental health conditions. It then addresses inequities in health services across those communities. It is argued that in addition to redressing the inequities in health services availability, prevention and health promotion can play an important part in reversing health inequities and improving health within regional, rural and remote communities. Improved ‘health literacy’ and lifestyle change are major contributors to health gains. The presentation concludes by drawing attention to the importance of continuing research, commitment to lifelong learning, evidence based practice, and strong university-community partnership in health promotion and health care delivery.